IGF-1 LR3 (1mg)

The Precision Growth Factor for Lean Muscle, Body Recomposition & Accelerated Recovery

IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a modified peptide version of naturally occurring IGF-1, structurally enhanced for increased potency and extended activity in your body. Unlike standard IGF-1 which is quickly bound by proteins and deactivated within minutes, IGF-1 LR3 has been precisely engineered with 13 additional amino acids and a strategic substitution at position 3 (arginine replacing glutamic acid). This modification reduces binding to IGF-binding proteins, allowing the peptide to remain active for 20-30 hours and deliver sustained anabolic signals directly to your muscle tissue.

For women seeking lean, sculpted muscle definition without bulk, targeted fat loss (especially stubborn areas), enhanced recovery that keeps pace with your training intensity, improved body composition during hormonal transitions, visible improvements in skin elasticity and firmness, or sustainable metabolic support that doesn't disrupt your hormonal balance—IGF-1 LR3 offers a uniquely effective, non-androgenic approach that works with your body's natural growth processes.

What makes IGF-1 LR3 particularly compelling for women is what it doesn't do: it's non-androgenic, meaning it won't cause masculinizing side effects like voice deepening, facial hair, or hormonal disruption. This peptide works through growth signaling pathways—not testosterone or estrogen—making it fundamentally safer for women who want performance enhancement without compromising their feminine physique or endocrine health.

What Women Use IGF-1 LR3 For

Body Composition & Lean Muscle Building

• Lean, defined muscle tone — particularly in glutes, shoulders, arms, and legs
• Muscle density without bulk — creates firm, sculpted appearance
• Body recomposition — simultaneous fat loss and muscle preservation
• No water retention or bloating — dry, tight muscle definition
• Stubborn fat reduction — particularly effective on areas resistant to diet alone
• Enhanced nutrient partitioning — calories directed to muscle, not fat storage
• Preservation of muscle during caloric deficit — ideal for cutting phases
• Feminine athletic physique — toned and strong, never bulky

Recovery & Performance Enhancement

• Dramatically accelerated recovery between training sessions — train more frequently without overtraining
• Reduced muscle soreness (DOMS) — wake up ready for your next workout
• Faster soft tissue repair — tendons, ligaments, connective tissue
• Joint comfort and reduced inflammation — especially valuable during menstrual cycle
• Enhanced training capacity — better endurance and work volume
• Injury recovery support — speeds healing from strains, sprains, and tissue damage
• Reduced recovery time post-childbirth or surgery
• Better adaptation to progressive overload

Skin Health & Anti-Aging Benefits

• Enhanced collagen synthesis — visibly firmer, more elastic skin
• Reduced appearance of fine lines and wrinkles
• Improved skin texture and radiance — often noticed by others before body composition changes
• Thicker, healthier hair growth
• Stronger, faster-growing nails
• Cellular regeneration — comprehensive anti-aging at tissue level
• Improved skin hydration and plumpness

Metabolic & Hormonal Health

• Improved insulin sensitivity — better blood sugar regulation
• Enhanced glucose uptake in muscle — fuel directed to performance, not fat storage
• Optimized fat metabolism (lipolysis) — mobilize stored fat for energy
• Support during perimenopause/menopause — counteract metabolic slowdown
• No hormonal disruption — works independently of estrogen/progesterone
• Sustainable long-term metabolic improvements

Energy & Overall Vitality

• Increased physical stamina and endurance
• Better workout performance and intensity tolerance
• Reduced fatigue, especially during caloric restriction
• Enhanced overall sense of vitality and strength
• Improved exercise recovery and adaptation

How IGF-1 LR3 Works

IGF-1 LR3 works through sophisticated cellular mechanisms that enhance your body's natural growth and repair processes:

Direct Muscle Growth Signaling: IGF-1 LR3 binds to IGF-1 receptors in muscle cells, activating the PI3K/Akt/mTOR pathway—the primary cellular mechanism for muscle protein synthesis and growth. This triggers satellite cell activation (muscle stem cells) which proliferate and differentiate, supporting both muscle repair and actual creation of new muscle fibers (hyperplasia). Unlike steroids which only enlarge existing muscle fibers, IGF-1 LR3 can create new muscle cells, leading to more sustainable, natural-looking muscle development.

Enhanced Protein Binding Efficiency: The structural modification in LR3 (Long R3) dramatically reduces its affinity to IGF-binding proteins (IGFBPs) that normally sequester natural IGF-1. While approximately 90% of your body's natural IGF-1 is bound and inactive, IGF-1 LR3 circulates more freely and remains bioavailable for 20-30 hours—versus just minutes for natural IGF-1. This means sustained, consistent anabolic signaling throughout the day.

Optimized Nutrient Partitioning: IGF-1 LR3 enhances glucose and amino acid uptake specifically in muscle tissue. This means the food you eat is preferentially directed toward muscle building and repair rather than fat storage. For women in a caloric deficit, this is particularly valuable—you preserve lean muscle while losing fat, creating the sculpted, toned physique most women desire.

Lipolysis (Fat Breakdown): IGF-1 LR3 stimulates the breakdown of stored body fat through enhanced lipolytic activity, particularly targeting stubborn adipose tissue. By improving how your body mobilizes and utilizes fat for energy, it supports leaner body composition even without extreme caloric restriction.

Anti-Catabolic Effect: One of IGF-1 LR3's most valuable properties is preventing muscle breakdown (catabolism), especially during caloric deficits, intense training periods, or hormonal fluctuations. This protective effect ensures you maintain hard-earned muscle while shedding fat—the holy grail of body recomposition.

Collagen Synthesis & Tissue Repair: IGF-1 LR3 doesn't just build muscle—it accelerates production of collagen and structural proteins throughout connective tissue, tendons, ligaments, and skin. This creates visible improvements in skin elasticity and firmness, supports joint health, and accelerates healing from soft tissue injuries. Many women report that skin improvements are among the first noticeable benefits.

Reduced Inflammation & Enhanced Recovery: By promoting cellular repair and reducing inflammatory markers, IGF-1 LR3 significantly shortens recovery time between workouts. This means you can train harder and more frequently without the typical soreness and fatigue that limits progress.

Synergy with Training & Nutrition: IGF-1 LR3 amplifies the results of your existing efforts. It doesn't replace proper training and nutrition—it makes them dramatically more effective. Every workout becomes more productive; every meal contributes more efficiently to your goals.

No Ghrelin Stimulation: Unlike some growth peptides (GHRP-2, GHRP-6), IGF-1 LR3 doesn't stimulate appetite through ghrelin receptors. This makes it ideal for women focused on fat loss without battling increased hunger.

Realistic Perspective: IGF-1 LR3 provides genuine, measurable benefits that develop progressively over 4-8 weeks. This is precision enhancement—not magic. Results require consistent dosing, proper training, adequate nutrition (especially protein), and patience. The women who see the most dramatic results are those who view IGF-1 LR3 as a powerful tool within a comprehensive strategy, not a shortcut around fundamentals.

Who This Is For

IGF-1 LR3 may be appropriate if you:

• Want to build lean, feminine muscle tone without bulky mass
• Are focused on body recomposition (losing fat while building/preserving muscle)
• Need enhanced recovery to support frequent training
• Train intensely and want to maximize your results
• Are experiencing age-related metabolic slowdown or body composition changes
• Want to improve muscle definition and reduce stubborn body fat
• Are in perimenopause/menopause and struggling with body composition shifts
• Seek skin quality and anti-aging benefits alongside performance enhancement
• Value non-hormonal, non-androgenic enhancement options
• Are committed to proper training and nutrition (IGF-1 LR3 amplifies effort, doesn't replace it)
• Have realistic expectations about progressive, sustainable results
• Are comfortable with daily subcutaneous injections
• Want to preserve muscle during a cutting phase or caloric deficit
• Are recovering from injury and want to support tissue repair

NOT recommended for:

• Women expecting results without training or proper nutrition
• Anyone with active cancer or history of cancer (IGF-1 promotes cell growth)
• Those who are pregnant, breastfeeding, or trying to conceive
• Women with uncontrolled diabetes (affects glucose metabolism)
• Anyone with known tumors or growths
• Those expecting rapid, dramatic transformation without consistent effort
• Women looking for appetite suppression alone (this enhances training results, not hunger control)
• Anyone under 25 with optimal natural IGF-1 levels (less benefit)
• Those unwilling to monitor blood glucose if sensitive or diabetic

Research Dosing Protocols

Standard Women's Dosing

Dose Range: 10-20mcg per injection (some experienced users up to 30mcg)
Frequency: Once daily
Timing: Post-workout (preferred) or morning (fasted state)
Duration: 4-6 week cycles, followed by equal time off

Women benefit from conservative dosing—typically 10-20mcg daily for 4-6 week cycles. Female physiology responds well to lower doses, and this approach minimizes side effects while maximizing results.

Common Protocols

Conservative Beginner Protocol:

• Dose: 10mcg once daily
• Best for: First-time users, assessing tolerance, women with lower body weight
• Duration: 4 weeks on, 4 weeks off
• Pros: Minimal side effects, affordable, effective introduction to IGF-1 LR3
• Expected Results: Enhanced recovery, subtle muscle tone improvements, initial fat loss

Standard Protocol (Most Popular):

• Dose: 15-20mcg once daily
• Best for: Experienced users, comprehensive body recomposition goals
• Duration: 4-6 weeks on, equal time off
• Pros: Optimal balance of results and safety, well-tolerated by most women
• Expected Results: Visible muscle definition, measurable fat loss, enhanced skin quality, significant recovery benefits

Advanced Protocol:

• Dose: 20-30mcg once daily
• Best for: Very experienced users, athletes, aggressive body recomposition
• Duration: 4-6 weeks maximum, followed by 6-8 weeks off
• Pros: Maximum results for those who've demonstrated tolerance
• Cons: Higher side effect risk, diminishing returns above 20mcg for many women
• Note: Most women achieve excellent results at 15-20mcg; higher doses aren't always better

Optimal Timing

Post-Workout (Preferred for Most Women):

• Inject within 30-60 minutes after training
• Capitalizes on exercise-induced insulin sensitivity and nutrient uptake
• Maximizes muscle protein synthesis and recovery
• Reduces hypoglycemia risk (you'll eat post-workout)
• Most effective for muscle building and body recomposition goals

Morning (Fasted State - Alternative):

• Inject upon waking, 15-30 minutes before eating
• Ideal for enhanced fat burning during fasted cardio
• Maximizes IGF-1 receptor sensitivity
• CRITICAL: Have fast-acting carbs available (fruit, juice) in case of low blood sugar
• Best for women prioritizing fat loss

Avoid Evening/Bedtime Dosing:

• Unlike Sermorelin which benefits from nighttime dosing, IGF-1 LR3 can cause hypoglycemia during sleep
• Post-workout or morning dosing is significantly safer

Administration

• Method: Subcutaneous injection (abdomen, thigh, hip, or targeted muscle area for localized effect)
• Injection Technique: Rotate sites religiously to prevent lipohypertrophy
• Empty Stomach: Not required for IGF-1 LR3 (unlike Sermorelin), but fasted state enhances fat loss
• Post-Injection: Consume balanced meal with protein and carbs within 30-60 minutes to support muscle synthesis and prevent low blood sugar

Cycling Requirements

CRITICAL: Unlike Sermorelin which can be used continuously, IGF-1 LR3 should not exceed 6-8 weeks of continuous use without a break, as prolonged elevation may cause receptor desensitization or insulin sensitivity issues.

Recommended Cycle Structure:

• Cycle Length: 4-6 weeks maximum
• Off Period: Equal to on-period minimum (e.g., 4 weeks on = 4 weeks off minimum)
• Why Cycling Matters: Prevents receptor downregulation, maintains insulin sensitivity, allows natural IGF-1 production to normalize
• Long-Term Approach: Multiple cycles per year (e.g., 3-4 cycles annually) with proper off-periods

Reconstitution

Mix 1mg with 1ml bacteriostatic water:

• 1mg in 1ml = each 0.01ml (1 unit on insulin syringe) contains 10mcg

Dosing Measurements:

• For 10mcg dose = 0.01ml (1 unit)
• For 15mcg dose = 0.015ml (1.5 units)
• For 20mcg dose = 0.02ml (2 units)
• For 30mcg dose = 0.03ml (3 units)

[View our reconstitution calculator →]

Vial Yield: 1mg vial provides approximately 50-100 doses depending on protocol (20mcg = 50 doses, 10mcg = 100 doses). Most women purchase 2-3 vials per 4-6 week cycle.

Stacking Considerations

IGF-1 LR3 + Sermorelin (or CJC-1295 + Ipamorelin):

• Comprehensive growth hormone optimization
• Sermorelin at night (GH release); IGF-1 LR3 post-workout (direct anabolic signaling)
• Synergistic effects on body composition, recovery, and anti-aging
• Most effective stack for overall physique transformation

IGF-1 LR3 + BPC-157 or TB-500:

• Ultimate recovery and healing stack
• IGF-1 LR3 for muscle growth and systemic benefits; BPC-157/TB-500 for targeted injury repair
• Separate injection sites
• Ideal for athletes or women recovering from injury

IGF-1 LR3 + GHK-Cu:

• Enhanced skin and anti-aging focus
• Amplified collagen production and cellular repair
• Visible aesthetic improvements
• Separate injections, can be same timing

IGF-1 LR3 + AOD-9604:

• Advanced fat loss stack
• Complementary fat-burning mechanisms
• Monitor for excessive lipolysis (can increase fatigue if undereating)

What NOT to Combine:

• Avoid stacking with synthetic growth hormone (HGH)—IGF-1 LR3 is the alternative, not an addition
• Be cautious combining multiple glucose-affecting peptides if diabetic or insulin-sensitive
• Don't stack with other peptides that significantly impact blood sugar without medical supervision

What's Included

✓ 1 vial of IGF-1 LR3 - 1mg sterile lyophilized powder
✓ Batch number clearly labeled on vial
✓ Certificate of Analysis (COA) - Third-party verified [Download →]
✓ Purity: ≥98% (HPLC tested)
✓ Correct peptide sequence verified (83 amino acids with Long R3 modification)
✓ Sterile sealed vial for safe storage
✓ Comprehensive dosing guide with purchase

Not included: Bacteriostatic water, insulin syringes, alcohol swabs (available separately)

Note: 1mg provides 50-100 doses depending on protocol. Most women use 2-3 vials per cycle (4-6 weeks).

Storage & Handling

Before Reconstitution

• Store in freezer (-20°C) or refrigerator (2-8°C)
• Avoid light exposure
• Shelf life: 2+ years when properly stored

After Reconstitution

• MUST be refrigerated (2-8°C) immediately
• Use within 30 days maximum
• Never freeze once mixed
• Protect from light (store in box or wrapped in foil)
• Peptides degrade rapidly with heat and light

Handling Tips

• Allow refrigerated solution to reach room temperature before injecting (5-10 min) for comfort
• Wipe vial top with alcohol before each draw
• Use new needles for each injection
• Rotate injection sites consistently
• Can be at room temperature briefly during preparation

Side Effects & What to Expect

Common Side Effects

Hypoglycemia (Low Blood Sugar) - MOST IMPORTANT:

• Because IGF-1 mimics insulin, it increases glucose uptake into cells, which can cause hypoglycemia symptoms: shakiness, fatigue, dizziness, sweating, irritability
• Prevention: Always have fast-acting carbs available (fruit juice, glucose tabs, fruit)
• Inject post-workout or consume carbs + protein within 30-60 minutes after injection
• More common with higher doses or fasted-state dosing
• If you feel symptoms, immediately consume 15-20g fast-acting carbs

Injection Site Reactions (Common, Manageable):

• Mild redness, slight irritation at injection site
• Usually minimal with proper rotation technique
• Rare with subcutaneous delivery vs intramuscular
• Solution: Rotate sites religiously, use sterile technique

Temporary Water Retention (Mild, Less Common Than With GH):

• Slight fluid retention, particularly in hands/fingers
• Temporary weight fluctuation (1-3 lbs water)
• Much less pronounced than with growth hormone peptides
• Usually resolves within 1-2 weeks
• Reduce sodium if bothersome

Joint Discomfort (Rare at Proper Doses):

• Mild joint achiness or stiffness (uncommon at women's doses)
• If occurs, reduce dose by 5mcg
• More common when doses exceed 20mcg or in older users

Headaches (Mild, Temporary):

• Occasional mild headaches in first week
• Related to changes in fluid balance and cellular activity
• Typically resolve as body adapts
• Stay well-hydrated; reduce dose if persistent

What You WILL Notice

Within Days:

• Enhanced recovery from workouts—less soreness, faster bounce-back
• Improved muscle pump during training
• Better energy and workout performance
• Subtle improvements in how muscles feel (fuller, firmer)

Within 1-2 Weeks:

• Visible reduction in muscle soreness (DOMS)
• Noticeably faster recovery between training sessions
• Skin beginning to look more hydrated and radiant
• Improved muscle definition when flexed
• Better training capacity and endurance

Within 3-4 Weeks:

• Clear visible changes in body composition—leaner, more defined
• Stubborn fat areas beginning to reduce
• Muscle tone becoming more apparent
• Skin quality improvements (elasticity, firmness)
• Friends/family commenting on your appearance
• Clothes fitting differently (smaller in waist/hips, defined in shoulders/arms)

Within 4-6 Weeks (Full Cycle):

• Significant body recomposition—obvious fat loss and muscle definition
• Enhanced muscle tone in glutes, shoulders, arms, legs
• Visible skin improvements—fewer fine lines, better texture
• Hair and nails growing faster and stronger
• Sustained energy and performance
• Overall more sculpted, athletic physique

What You WON'T Experience (Major Advantage for Women)

• No masculinization effects — voice, facial hair, body hair changes (not androgenic)
• No hormonal disruption — doesn't affect menstrual cycle, estrogen, progesterone
• No appetite stimulation — won't make fat loss harder with increased hunger
• No significant water retention — creates dry, defined muscle (unlike GH peptides)
• No testosterone suppression — works independently of sex hormones

Managing Side Effects

Hypoglycemia:

• Never inject in a fasted state without carbs available
• Post-workout injection timing is safest
• Have glucose source readily accessible
• Reduce dose if symptoms persist

Injection Site Irritation:

• Rotate sites meticulously
• Ensure proper sterile technique
• Allow solution to reach room temp before injecting

Joint Discomfort:

• Reduce dose by 5mcg
• Ensure adequate hydration
• Consider adding collagen supplementation

Water Retention:

• Reduce sodium intake
• Increase potassium-rich foods (avocado, banana, spinach)
• Stay patient—typically temporary
• Ensure you're cycling properly (not using continuously)

Serious Concerns (Rare at Proper Doses & Cycling)

• Not recommended with active cancer (IGF-1 promotes cell growth)
• Prolonged use without cycling may cause organ enlargement (heart, intestines), though this is associated with excessive doses and continuous use without breaks
• Monitor blood sugar closely if diabetic or prediabetic
• Discontinue use if unusual tissue growth or pain occurs

Safety Profile

IGF-1 LR3 is non-androgenic, meaning it won't cause testosterone suppression, doesn't aromatize into estrogen, and carries no direct androgenic side effects. This makes it one of the safer enhancement options for women. The key to safety is proper dosing, strict cycling protocols, and responsible monitoring—especially of blood glucose.

Timeline & Results

Week 1-2: Foundation & Recovery

Initial benefits center on recovery. You'll notice significantly less muscle soreness after workouts—DOMS (delayed onset muscle soreness) is dramatically reduced. You're bouncing back faster between training sessions, allowing you to increase training frequency or intensity. Energy during workouts improves. Muscles feel fuller and more responsive. Some women notice very subtle changes in how their body looks when flexed. If hypoglycemia occurs, it's typically during this adaptation period.

Week 3-4: Visible Transformation Begins

This is when body composition changes become obvious. Fat loss is clearly visible, especially in areas you've struggled with (lower abdomen, hips, thighs, back of arms). Muscle definition is emerging—you can see more separation and tone. Skin is noticeably more radiant and hydrated—this is often the first thing others comment on. Training performance is excellent; you're lifting heavier or training longer with better recovery. You feel leaner, tighter, and more athletic. Clothes fit differently (looser in waist, more fitted in shoulders/glutes).

Week 4-6 (End of Cycle): Peak Results

By the end of your cycle, transformation is significant and undeniable. You've achieved measurable fat loss (typically 3-6 lbs of pure fat, though scale weight may not reflect this if you've built muscle). Lean muscle tone is dramatically improved—defined arms, sculpted shoulders, toned legs, visible glute development. Skin quality is enhanced—firmer, more elastic, reduced fine lines, overall "glow." Hair and nails are growing faster and healthier. Your physique looks more athletic, sculpted, and feminine. Recovery remains exceptional. You feel strong, vital, and confident in your body.

Off-Cycle (4-6 Weeks): Maintaining Results

When you cycle off, most of your muscle and body composition gains are maintained if you continue training and eating properly. Skin benefits remain visible. Recovery returns to normal baseline (still good if you're training well, just not as enhanced). This off-period allows your IGF-1 receptors to resensitize and your natural systems to normalize. You won't lose your results during off-periods—they're sustainable gains, not temporary water or glycogen.

Multiple Cycles (Long-Term): Progressive Transformation

With repeated cycles throughout the year (e.g., 3-4 cycles annually with proper off-periods), you continue making progressive improvements. Each cycle builds on previous gains. Your body composition reaches new baseline levels—leaner, more muscular, more defined. Long-term metabolic benefits accumulate (better insulin sensitivity, optimized nutrient partitioning). Skin quality continues improving with each cycle. Many women report their best physique ever after 2-3 properly executed cycles over 6-12 months.

Important Reality Check

• Results absolutely require proper training (3-5x per week resistance training recommended)
• Nutrition must support your goals—adequate protein (0.8-1g per lb bodyweight), slight caloric deficit for fat loss
• Individual response varies based on training experience, genetics, baseline body composition, age
• Consistency is essential—missing injections reduces effectiveness significantly
• This is a powerful tool that amplifies your efforts—it doesn't replace fundamentals
• The best results come from viewing IGF-1 LR3 as part of a comprehensive strategy, not a standalone solution
• Women who track their training (weights, reps, measurements, photos) see the most dramatic documented progress

Stacking & Combinations

IGF-1 LR3 + Sermorelin (or CJC-1295 + Ipamorelin) - THE ULTIMATE STACK

This is the most comprehensive growth hormone optimization protocol for women. Sermorelin at night stimulates natural GH pulses; IGF-1 LR3 post-workout provides direct anabolic signaling. Synergistic effects across ALL benefits—body composition, recovery, sleep, skin, anti-aging, metabolism. Can be combined with both for maximum transformation. This stack delivers results that neither peptide achieves alone.

Protocol:

• Sermorelin 200-250mcg before bed (on empty stomach)
• IGF-1 LR3 15-20mcg post-workout daily
• Most effective combination for comprehensive physique transformation

IGF-1 LR3 + BPC-157 or TB-500

Comprehensive recovery and injury healing stack. IGF-1 LR3 for systemic muscle growth and anabolic benefits; BPC-157 or TB-500 for targeted tissue repair, tendon/ligament healing, and anti-inflammation. Separate injection sites. Exceptional for athletes with nagging injuries or women recovering from surgery. No negative interactions.

IGF-1 LR3 + GHK-Cu

Enhanced anti-aging and aesthetic stack. Both peptides amplify collagen production and skin quality. IGF-1 LR3 provides systemic effects; GHK-Cu adds additional tissue repair and antioxidant support. Popular among women prioritizing skin and anti-aging alongside body composition. Separate injections.

IGF-1 LR3 + AOD-9604 or Tesamorelin

Advanced fat loss focus. Multiple mechanisms for lipolysis and fat mobilization. Effective for stubborn fat areas or aggressive cutting phases. Monitor closely for excessive fat loss symptoms (fatigue, hormonal disruption). Experienced users only.

IGF-1 LR3 + NAD+ Boosters (NMN, NR)

Cellular energy optimization plus anabolic growth signaling. NAD+ supports mitochondrial function and energy production; IGF-1 LR3 directs that energy toward muscle building and recovery. Synergistic for performance, vitality, and longevity. Take NAD+ boosters orally daily; dose IGF-1 LR3 as usual.

What NOT to Combine

• Don't use IGF-1 LR3 with synthetic growth hormone (HGH)—they're alternatives, not additions
• Avoid combining with other glucose-affecting compounds without medical monitoring
• Be very cautious stacking with multiple peptides if diabetic or insulin-resistant
• Don't combine with appetite-stimulating peptides (GHRP-2, GHRP-6) if fat loss is your goal

Frequently Asked Questions

How is IGF-1 LR3 different from Sermorelin or growth hormone?
Sermorelin stimulates your pituitary to release growth hormone, which then signals your liver to produce IGF-1. IGF-1 LR3 provides the growth factor directly, bypassing the GH step entirely. This makes it more targeted for muscle-building and recovery, while Sermorelin offers broader benefits including enhanced sleep. They work synergistically when stacked.

Will I look bulky or masculine?
Absolutely not. IGF-1 LR3 is non-androgenic and won't cause masculinization—no voice changes, facial hair, or hormonal disruption. Women lack the testosterone needed for bulky muscle growth. IGF-1 LR3 creates lean, defined, feminine muscle tone—sculpted and athletic, not bulky.

How long until I see results?
Recovery benefits within days. Visible body composition changes by weeks 2-3. Dramatic transformation by weeks 4-6. Skin improvements become obvious around week 3-4. Be patient—this is progressive, sustainable change.

Can I lose fat without changing my diet?
Very unlikely. IGF-1 LR3 makes fat loss MORE effective, but you still need a caloric deficit. It optimizes nutrient partitioning, preserves muscle during dieting, and enhances fat mobilization—but it can't overcome poor nutrition. Diet remains foundational.

Why do I need to cycle off?
Continuous use beyond 6-8 weeks can cause receptor desensitization and may affect insulin sensitivity. Cycling allows your natural IGF-1 system to normalize, maintains effectiveness, and prevents potential side effects from chronic elevation. This isn't optional—proper cycling is critical for safety and sustained results.

What if I experience low blood sugar?
Immediately consume 15-20g fast-acting carbs (fruit juice, glucose tabs, fruit). Symptoms should resolve within 10-15 minutes. For future injections, ensure you eat within 30-60 minutes, or switch to post-workout timing. If hypoglycemia persists, reduce dose by 5mcg.

Is this safe long-term?
When used with proper cycling (4-6 weeks on, equal time off), safety profile is favorable for healthy women. Long-term risks are primarily associated with continuous use without breaks or excessive dosing. Follow protocols, cycle properly, and IGF-1 LR3 can be used safely for multiple cycles per year.

Can I use this during perimenopause or menopause?
Yes—this is actually an excellent time. IGF-1 LR3 doesn't disrupt hormones and can help counteract age-related muscle loss, metabolic slowdown, and body composition changes common during hormonal transitions. Many women find it particularly effective during this life stage.

Will this affect my menstrual cycle?
No. IGF-1 LR3 works independently of reproductive hormones and doesn't directly impact estrogen, progesterone, or menstrual cycles. Some women report more consistent cycles due to overall improved health and reduced stress (from better recovery and body composition), but this isn't a direct effect.

Should I inject post-workout or morning?
Post-workout is optimal for most women—capitalizes on exercise-induced nutrient uptake, maximizes muscle building, reduces hypoglycemia risk. Morning fasted can work for fat loss emphasis but requires caution with blood sugar. Choose based on your primary goal and tolerance.

How much will this cost per cycle?
At 15-20mcg daily for 4-6 weeks, you'll need 2-3 vials per cycle. Calculate based on dosing and vial cost. Most women budget for 2-3 vials when planning a cycle.

Will my skin really improve?
Yes. IGF-1 increases collagen synthesis and cell turnover, which improves skin elasticity, reduces fine lines, and creates better texture. Results aren't immediate (3-4+ weeks) but are genuine and frequently commented on by others.

Can I travel with this?
Reconstituted IGF-1 LR3 requires refrigeration, making travel challenging without cooler packs. Unreconstituted powder is more travel-friendly but still needs cool storage. Plan accordingly or take breaks during travel.